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Velu U.


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EGFR expression and the role of Gefitinib in Oral cavity lesions Prasad A. Velu U.
EGFR expression and the role of Gefitinib in Oral cavity lesions
Oral Cavity cancer is the 10th most common malignancy globally. EGFR is a glycoprotein encoded by a gene located on chromosome 7p12. Stimulation of EGFR will activate an intracellular signalling pathway, leading to the inhibition of apoptosis, activation of cell proliferation and angiogenesis, as well as an increase in metastatic spread potential....
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