A series of Ethyl-3-methyl-5-(substituted-phenyl)-6,7,8,9-tetrahydro-5H-thiazolo[2,3-b]quinazoline-2-carboxylate derivatives have been synthesize from cyclohexanone and substituted benzaldehyde with the aim of developing potential antimicrobials and antitubercular agents. It was characterized by FT-IR, 1H NMR and Mass spectroscopy....

A detailed review on HIV and its drugs was prepared. This broad spectrum of biochemical targets has been facilitated by the synthetic versatility of heterocyclic compounds, which has allowed the generation of a large number of structurally diverse derivatives....

Nitrogen containing synthetically and biologically important heterocyclic ring system namely pyrimidine have been reviewed. Based on review the pyrimidine derivatives will obtained by the various condensation methods. The structures of these compounds will evident by elemental analysis such as, IR, 1H NMR and mass spectral analysis....

A varicose vein is a venous disorder and the word varicose comes from the Latin word “varix” (meaning “twisted”). Up to 25 % of women and 18 % of men will suffer from varicose veins. Nearly 50 % of untreated patients eventually experiences chronic venous insufficiency. Varicose veins are more common in women than men....

In the present study, we have reported the effect of thiazole based derivatives as potent anticancer agents. The review report helps to elucidate further the structure activity relationship (SAR) studies on the anticancer activity of thiazole moiety....

A variety of five membered N-heterocyclic derivatives have been reviewed. Based on brief review, the compounds have been subjected for assessment of their pharmacological activities, and it’s believed that these compounds found to be the most active for their further studies....

Tuberculosis remains primary cause of comparatively high mortality worldwide. The statistics highlighted that three million people worldwide die annually from complication of TB and there are estimated 8 million of new cases each year, and today more people die from tuberculosis than ever before....

A variety of imidazole, and fused imidazole derivatives have been reviewed. Continuous efforts on combination of lead optimization and molecular modeling studies in synthesis and the structure activity relationship studies and biological activities of novel modi?ed imidazole, and fused imidazole derivatives, allowed to identi?...

Naproxen is chemically, (2S)-2-(6-methoxy naphthalen-2-yl) propanoic acid. It is a propionic acid derivative related to the aryl acetic acid group of non-steroidal anti-inflammatory drugs. It is a non-steroidal anti-inflammatory drug (NSAID) commonly used for the reduction of moderate to severe pain, fever, inflammation and stiffness....

A variety of novel pyrimidine, thiosemicarbazide and semicarbazide derivatives have been reviewed. Based on brief review of compounds will be subject to in vitro assessment for their antitumor and antimicrobial activities, and compounds are believed to be the most active members in this study....

Review is a major component to carry out the research work. The review on quinazoline, substituted amine, semicarbazide derivatives furnishes its established biological activities. Thus quinazoline scaffold is not only synthetically important but also possesses a wide range of promising biological activities....

From detailed literature survey, various techniques are now a days available for determination of Naproxen and Sumatriptan in bulk as well as in dosage forms. Also methods are made available for estimation of these drugs in plasma. Among the different methods available HPLC and UV spectroscopy has gained considerable importance and are widely used....

This review has been aimed at the treatment of rheumatoid arthritis and their significance. Rheumatoid arthritis is the most important systemic disease. The current review information has been found to reveal both remarkable active medicine and a variety of valuable practical applications....

The number compounds have been prepared in order to improve the pharmacological pro?les of antihyperglycemic activity. The series of 3-benzyl-2-(4\'-substituted phenyl)-4(5H)-(4\'\'-nitrophenyl amino)-1, 3-oxazolidines 6a-e were tested against hyperglycemic activity....

These novel ‘‘one’’ and ‘‘thione’’ derivatives were synthesized by using established methods and were characterized by IR, 1H NMR and Mass spectroscopy in order to confirm their formation. These compounds were synthesized to screen for their antibacterial, antifungal and antitubercular activities....